Recent Development of Benzotriazole-based Medicinal Drugs

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Recent Development of Benzotriazole-based Medicinal Drugs

Azole heterocyclic compounds exhibit wide range of medicinal applications in the treatment of various types of diseases [1]. Especially, triazole derivatives as medicinal drugs have been playing important roles in medicinal chemistry [2-4], and a lot of triazole analogs including imidazole [5], thiazole [6], carbazole [7,8], oxazole [9] and benzimidazole [10,11], etc. have also been found to be...

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Development of anti-malaria herbal preparation / drugs from local medicinal plants

1. The screening for potential anti-malaria properties by bioassay guided fractionations. The biological properties were carried out using the plasmodium lactate dehydrogenase assay (pLDH) (Makler, 1993). 2. The harmful effect of the extract was determined by the MTT assay (Mossman, 1983). 3. The extracts were tested for its efficacy in animal model using rodent malaria parasite, P. berghei usi...

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ژورنال

عنوان ژورنال: Medicinal Chemistry

سال: 2014

ISSN: 2161-0444

DOI: 10.4172/2161-0444.1000207